A novel infectious coronavirus disease (COVID-19) identified in late 2019 has now been labelled as a global pandemic by World Health Organization (WHO). The COVID-19 outbreak has shown some positive impacts on the natural environment. In present work, India is taken as a case study to evaluate the effect of lockdown on air quality of three Indian cities. The variation in concentration of key air pollutants including PM10, PM2.5, NO2, SO2 and O3 during two phases, pre-lockdown and post-lockdown phases, was analysed. The concentration of PM10, PM2.5, NO2 and SO2 reduced by 55%, 49%, 60% and 19%, and 44%, 37%, 78% and 39% for Delhi and Mumbai, respectively, during post-lockdown phase. Overall, the findings in present study may provide confidence to the stakeholders involved in air quality policy development that a significant improvement in air quality can be achieved in future if better pollution control plans are strictly executed.