Abstract The atmospheric CO 2 growth rate is a fundamental measure of climate forcing. NOAA's growth rate estimates, derived from in situ observations at the marine boundary layer (MBL), serve as the benchmark in policy and science. However, NOAA's MBL‐based method encounters challenges in accurately estimating the whole‐atmosphere CO 2 growth rate at sub‐annual scales. Here we introduce the Growth Rate from Satellite Observations (GRESO) method as a complementary approach to estimate the whole‐atmosphere CO 2 growth rate utilizing satellite data. Satellite CO 2 observations offer extensive atmospheric coverage that extends the capability of the current NOAA benchmark. We assess the sampling errors of the GRESO and NOAA methods using 10 atmospheric transport model simulations. The simulations generate synthetic OCO‐2 satellite and NOAA MBL data for calculating CO 2 growth rates, which are compared against the global sum of carbon fluxes used as model inputs. We find good performance for the NOAA method (R = 0.93, RMSE = 0.12 ppm year −1 or 0.25 PgC year −1 ). GRESO demonstrates lower sampling errors (R = 1.00; RMSE = 0.04 ppm year −1 or 0.09 PgC year −1 ). Additionally, GRESO shows better performance at monthly scales than the NOAA method (R = 0.76 vs. 0.47, respectively). Due to CO 2 's atmospheric longevity, the NOAA method accurately captures growth rates over 5‐year intervals. GRESO's robustness across partial coverage configurations (ocean or land data) shows that satellites can be promising tools for low‐latency CO 2 growth rate information, provided the systematic biases are minimized using in situ observations. Along with accurate and calibrated NOAA in situ data, satellite‐derived growth rates can provide information about the global carbon cycle at sub‐annual scales.