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NT
Natsuki Takano
Author with expertise in Mammalian MAP Kinase Signaling Pathways
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Open Access Advocate
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h-index:
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Induction of resistance to neurotrophic tropomyosin‐receptor kinase inhibitors by
HMGCS2
via a mevalonate pathway
Yasuhiro Kato
et al.
Jun 1, 2024
A neurotrophic tropomyosin receptor kinase (NTRK)-tyrosine kinase inhibitor (TKI) has shown dramatic efficacy against malignant tumors harboring an NTRK fusion gene. However, almost all tumors eventually acquire resistance to NTRK-TKIs.
Genetics
Biochemistry
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