XDSAPP is a Tcl/Tk-based graphical user interface for the easy and convenient processing of diffraction data sets using XDS . It provides easy access to all XDS functionalities, automates the data processing and generates graphical plots of various data set statistics provided by XDS . By incorporating additional software, further information on certain features of the data set, such as radiation decay during data collection or the presence of pseudo-translational symmetry and/or twinning, can be obtained. Intensity files suitable for CCP4 , CNS and SHELX are generated.