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Vadym Sham

Author with expertise in Role of Fluorine in Medicinal Chemistry and Pharmaceuticals

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Publications

Saturated F2‐rings from Alkenes

Honggen Wang et al.Jan 14, 2025

A general method to convert simple exocyclic alkenes (no Ar‐substituents) into saturated F2‐rings has been developed. The reaction involves the IIII‐reagent C6F5I(OAc)2 (F5‐PIDA). The reaction efficiently works on the mg‐, g‐, and even multigram scale.

Inorganic Chemistry

Pharmaceutical Science

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Inorganic Chemistry

Pharmaceutical Science

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Saturated F2‐rings from Alkenes

Honggen Wang et al.Jan 14, 2025

A general method to convert simple exocyclic alkenes (no Ar‐substituents) into saturated F2‐rings has been developed. The reaction involves the IIII‐reagent C6F5I(OAc)2 (F5‐PIDA). The reaction efficiently works on the mg‐, g‐, and even multigram scale.

Organic Chemistry

0

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Organic Chemistry

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