High Prevalence of F2 20210G > A in Splanchnic Vein Thrombosis and Cerebral Venous Sinus Thrombosis: A Retrospective Cohort Study of Patients with Thrombosis in Atypical Sites

Does the introduction clearly articulate the research question and provide adequate context? Is the study's significance within the field convincingly established?

Does the study design test the authors' hypothesis? Are the methods described in enough detail for independent replication?

Were the study's findings analyzed and interpreted reasonably? Is the resulting data open and auditable? Are the figures of high resolution, describe data appropriately and adequately labelled? Please provide comments - positive or negative on each figure including supplementary ones.

Do the results support the authors’ conclusions? Are there any alternative interpretations of the study's findings that the authors should have considered?